Sol Zakay's Topland Group is aiming to deploy £250m of capital in the healthcare market this year.
The company aims to have a £600m portfolio by the end of the year, it said in its chairman's statement.
"Our diversification into the healthcare sector continued apace during 2017 with Topland Henley Healthcare Investments making over £100m of investments. We plan to continue to focus on the acquisition of singular and portfolio based residential assets," it said.
During 2018, Topland also intends to complete a refurbishment programme of its Hallmark hotel division, which incudes 27 directly operated hotels.
It is also focusing on providing senior, mezzanine and preferred equity finance. In 2017 its total lending activity exceeded the £1bn barrier having issued £300m of loans.
"I remain keen to deploy further venture capital to partners who have the experience and opportunity, but not the equity" Zakay said.
"Our business model ensures that we will always have significant cash reserves available to deploy when the right opportunities present themselves. This, alongside the quality and depth of in-house expertise, means that Topland will remain an active participant across the entire commercial real estate spectrum."